合法博彩网站

合法博彩网站,

鈥撎�听having regard to the draft Commission implementing decision renewing the authorisation for the placing on the market of products containing, consisting of or produced from genetically modified maize MON 88017 (MON-88脴17-3) pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (D069148/02),

鈥撎�听having regard to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council of 22听September 2003 on genetically modified food and feed(1), and in particular Articles 11(3) and 23(3) thereof,

鈥撎�听having regard to the vote of the Standing Committee on the Food Chain and Animal Health referred to in Article 35 of Regulation (EC) No听1829/2003, on 26 October 2020, at which no opinion was delivered,

鈥撎�听having regard to Articles听11 and 13 of Regulation (EU) No听182/2011 of the European 合法博彩网站 and of the Council of 16听February 2011 laying down the rules and general principles concerning mechanisms for control by Member States of the Commission鈥檚 exercise of implementing powers(2),

鈥撎�听having regard to the opinion adopted by the European Food Safety Authority (EFSA) on 21 April 2009, and published on 6 May 2009(3),

鈥撎�听having regard to the opinion adopted by EFSA on 29 January 2020, and published on 11 March 2020(4),

鈥撎�听having regard to its previous resolutions objecting to the authorisation of genetically modified organisms (鈥楪MOs鈥�)(5),

鈥撎�听having regard to Rule 112(2) and (3) of its Rules of Procedure,

鈥撎�听having regard to the motion for a resolution of the Committee on the Environment, Public Health and Food Safety,

A.听听whereas Commission Decision 2009/814/EC(6) authorised the placing on the market of food and feed containing, consisting of or produced from genetically modified (鈥楪M鈥�) maize MON听88017; whereas the scope of that authorisation also covers the placing on the market of products, other than food and feed, containing or consisting of GM maize MON 88017 for the same uses as any other maize, with the exception of cultivation;

B.听听whereas on 10 July 2018, Monsanto Europe N.V. on behalf of the authorisation holder Monsanto Company, United States, submitted to the Commission an application, in accordance with Articles 11 and 23 of Regulation (EC) No听1829/2003, for the renewal of that authorisation;

C.听听whereas, on 21 April 2009, EFSA adopted a favourable opinion, which was published on 6 May 2009, in relation to the initial authorisation application;

D.听听whereas, on 29 January 2020, EFSA adopted a favourable opinion, which was published on 11 March 2020, in relation to the renewal application;

E.听听whereas GM maize MON 88017 has been engineered to produce Cry3Bb1, a synthetic insecticidal protein (also known as a Bt toxin) with enhanced toxicity, compared to the natural bacteria it is derived from, against coleopteran insect pests and the CP4 EPSPS protein providing tolerance to glyphosate(7);

F.听听whereas the combination of the two gene constructs was derived from stacking, but no assessment was made of the single parental plants, in contravention of Commission Implementing Regulation (EU) No听503/2013(8);

G.听听whereas Regulation (EC) No听1829/2003 states that GM food or feed must not have adverse effects on human health, animal health or the environment, and requires the Commission to take into account any relevant provisions of Union law and other legitimate factors relevant to the matter under consideration when drafting its decision;

Member State concerns about the EFSA opinions

H.听听whereas, during the consultation period in relation to the initial authorisation application, Member States submitted many critical comments to EFSA鈥檚 draft opinion(9); whereas those critical comments include observations that little significance can be attributed to the acute toxicological tests which were undertaken with isolated proteins (i.e. not with the whole GM plant), that the proposed post-market environmental monitoring is too imprecise for a surveillance plan of unintended effects on human or animal health and the environment, that testing bacterial surrogate proteins should not substitute for testing the plant-expressed proteins, that the number of field seasons and locations is not adequate given the commercial use of the GMO, that further information is required to conclude on the risk assessment and that an increase in allergenic activity due to mCry3Bb1 protein in food and feed from GM maize MON 88017 cannot be excluded; whereas, furthermore, one Member State questioned the independence of the studies carried out for the purpose of the risk assessment, given that they were carried out by the applicant Monsanto;

I.听听whereas, during the consultation period in relation to the renewal application, Member States again submitted many critical comments to EFSA鈥檚 draft opinion(10); whereas those critical comments include the observation that the monitoring plan based on consent given by Decision 2009/814/EC and the monitoring reports have fundamental shortcomings and are not in in line with Directive 2001/18/EC of the European 合法博彩网站 and of the Council(11) or with relevant EFSA guidance, that the studies are not sufficient and that further experiments are needed to determine the exposure and subsequent effects and risks for non-target organisms from the exposure to Bt proteins via manure or sewage, and that due to missing information the environmental safety of GM maize MON 88017 cannot be fully assessed;

Complementary herbicides and lack of analysis of residues

J.听听whereas it has been shown that the cultivation of herbicide-tolerant GM crops results in a higher use of herbicides, which is due in large part to the emergence of herbicide-tolerant weeds(12); whereas, as a consequence, it has to be expected that crops of the GM maize will be exposed to both higher and repeated doses of glyphosate, which will potentially lead to a higher quantity of residues in the harvest;

K.听听whereas questions concerning the carcinogenicity of glyphosate remain; whereas EFSA concluded in November 2015 that glyphosate was unlikely to be carcinogenic and the European Chemicals Agency concluded in March 2017 that no classification was warranted; whereas, on the contrary, in 2015, the International Agency for Research on Cancer the specialised cancer agency of the World Health Organization, classified glyphosate as a probable carcinogen for humans; whereas a number of recent scientific peer-reviewed studies confirm the carcinogenic potential of glyphosate(13);

L.听听whereas according to an opinion by the EFSA Pesticides Unit data on glyphosate residues on GM maize with EPSPS modifications(14) are insufficient to derive maximum residue levels and risk assessment values(15);

M.听听whereas, again according to the EFSA Pesticides Unit, toxicological data allowing a consumer risk assessment to be performed for several break-down products of glyphosate relevant for GM glyphosate-tolerant crops are missing(16);

N.听听whereas assessment of herbicide residues, and herbicide break-down products, found on GM plants, along with their interaction with Bt toxins, is considered outside the remit of the EFSA GMO Panel and is therefore not undertaken as part of the authorisation process for GMOs; whereas this is problematic, since the way in which complementary herbicides are broken down by the GM plant concerned, and the composition and thus toxicity of the break-down products (鈥榤etabolites鈥�), can be driven by the genetic modification itself(17);

Invalid toxicity studies

O.听听whereas for the studies on acute toxicity and degradation in digestive fluids, the Cry3Bb1 and CP4 EPSPS proteins produced in a recombinant E. coli strain were used;

P.听听whereas, in general, little significance can be attributed to toxicological tests conducted with proteins in isolation, due to the fact that the effects of the protein in combination with the plant itself are not considered;

Q.听听whereas, for example, some plants, including maize, naturally produce proteinase inhibitors (PI) which have been shown to slow down the degradation of Bt toxins; whereas this results in much higher toxicity of the Bt toxin, if it is ingested together with the plant tissue, compared to the toxin in isolation; whereas a 1990 study, conducted by scientists at Monsanto, showed that even the presence of extremely low levels of PI enhanced the insecticidal activity of Bt toxins up to 20-fold(18); whereas this interaction has never been assessed, or mentioned, by EFSA in its risk assessments of GM Bt plants;

R.听听whereas it has been shown that factors which enhance the toxicity of the Bt toxins can also impact their selectivity(19): if efficacy of the Bt toxin on target organisms is increased, its selectivity may also be decreased and a wider range of non-target organisms may become susceptible; whereas, whilst no systematic research has been undertaken to date, several studies indicate the effects of PI combined with Bt toxins on non-target insects(20);

S.听听whereas the risk of higher toxicity to humans and mammals due to interaction between PI and Bt toxins in GM plants, is not known;

Questions of Bt adjuvanticity

T.听听whereas a number of studies show that side effects have been observed that may affect the immune system following exposure to Bt toxins and that some Bt toxins may have adjuvant properties(21), meaning that they can increase the allergenicity of other proteins with which they come into contact;

U.听听whereas the risk assessment performed by EFSA does not take into account the fact that maize produces PI(22) and therefore a much slower degradation of the Bt toxin has to be assumed if it is ingested with the plant material, compared to its isolated form; whereas this difference can also enhance its adjuvanticity and renders studies using isolated proteins invalid; whereas no empirical studies were performed to investigate the actual immunogenicity of the Bt toxin produced by the GM plant; whereas, the degradation in digestive fluids, which can be relevant for toxicity and adjuvanticity, was tested by using the Bt toxin in isolation;

Bt crops: effects on non-target organisms and increased resistance

V.听听whereas, unlike the use of insecticides, where exposure is at the time of spraying and for a limited time afterwards, the use of Bt crops leads to continuous exposure of the target and non target organisms to Bt toxins;

W.听听whereas the assumption that Bt toxins exhibit a single target specific mode-of-action can no longer be considered correct and effects on non-target organisms cannot be excluded(23); whereas an increasing number of non-target organisms are reported to be affected in many ways; whereas 39 peer-reviewed publications that report significant adverse effects of Bt toxins on many 鈥榦ut-of-range鈥� species are mentioned in a recent overview(24);

X.听听whereas combinatorial effects such as combination with PI may significantly contribute to the toxicity of Bt toxins; whereas the question of selectivity is especially relevant for synthetic Bt toxins, such as Cry3Bb1, which may show lower selectivity in combination with higher toxicity; whereas EFSA still considers that Bt toxins only affect a narrow range of non-target organisms, not taking into account any combinatorial effects; whereas a wider range of non-target organisms might be exposed to Bt toxins via spillage, waste and manure;

Y.听听whereas the risk assessment did not consider the development of resistance in the target pests to Bt toxins, possibly resulting in the use of less environmentally safe pesticides or increased doses and the number of applications to the GM crop in the country of cultivation; whereas, the US Environmental Protection Agency is proposing to phase out many current Bt corn hybrids, as well as some Bt cotton varieties, in the next three to five years, due to the growth in insect resistance to these crops(25);

Z.听听whereas, whilst it has been claimed that the use of Bt crops leads to a decrease in the use of insecticides, a recent study published in the United States(26), found that 鈥榮everal analyses on the influence of Bt crops on pesticide-use patterns do not seem to have considered seed treatments and so may have overstated reductions in insecticide use (especially 鈥榓rea treated鈥�) associated with Bt crops鈥�; whereas the same study finds that neonicotinoid seed treatments are often used in conjunction with Bt maize and soybean crops, that 鈥榌t]his pattern of use may have unintended consequences, namely resistance in target pests, outbreaks of non-target pests, and pollution with detrimental effects cascading to wildlife.鈥� The study also found that 鈥榮ome of these effects have already emerged鈥�; whereas the Union has banned the outdoor use of three neonicotinoids, including as seed coatings, because of their impact on honeybees and other pollinators(27);

AA.听听whereas the Union is party to the UN Convention of Biological Diversity (鈥楿N CBD鈥�), which obliges both importing and exporting countries to take biodiversity into account;

Undemocratic decision-making

AB.听听whereas the vote on 26 October 2020 of the Standing Committee on the Food Chain and Animal Health referred to in Article 35 of Regulation (EC) No听1829/2003 delivered no opinion, meaning that the authorisation was not supported by a qualified majority of Member States;

AC.听听whereas the Commission recognises that the fact that GMO authorisation decisions continue to be adopted by the Commission without a qualified majority of Member States in favour, which is very much the exception for product authorisations as a whole but which has become the norm for decision-making on GM food and feed authorisations, is problematic;

AD.听听whereas, in its eighth term, 合法博彩网站 adopted a total of 36 resolutions objecting to the placing on the market of GMOs for food and feed (33 resolutions) and to the cultivation of GMOs in the Union (three resolutions); whereas, to date, 合法博彩网站 has adopted eleven objections in its ninth term; whereas there was not a qualified majority of Member States in favour of authorising any of those GMOs; whereas despite its own acknowledgement of the democratic shortcomings, the lack of support from Member States and the objections of 合法博彩网站, the Commission continues to authorise GMOs;

AE.听听whereas, under Regulation (EU) No听182/2011, the Commission may decide not to authorise a GMO when there is no qualified majority of Member States in favour in the Appeal Committee(28); whereas no change of law is required in this respect;

1.听听Considers that the draft Commission implementing decision exceeds the implementing powers provided for in Regulation (EC) No听1829/2003;

2.听听Considers that the draft Commission implementing decision is not consistent with Union law, in that it is not compatible with the aim of Regulation (EC) No听1829/2003, which is, in accordance with the general principles laid down in Regulation (EC) No听178/2002 of the European 合法博彩网站 and of the Council(29), to provide the basis for ensuring a high level of protection of human life and health, animal health and welfare, and environmental and consumer interests, in relation to GM food and feed, while ensuring the effective functioning of the internal market;

3.听听Calls on the Commission to withdraw its draft implementing decision;

4.听听Welcomes the fact that the Commission finally recognised, in a letter of 11 September 2020 to Members, the need to take sustainability into account when it comes to authorisation decisions on GMOs(30); expresses its strong disappointment, however, that, on 28 September 2020, the Commission authorised another GM soybean for import(31) despite an objection by 合法博彩网站 and a majority of Member States voting against;

5.听听Calls on the Commission to move forward with the utmost urgency concerning the development of sustainability criteria, with full involvement of 合法博彩网站; calls on the Commission to provide information on how this process will be undertaken and in what timeframe;

6.听听Urges the Commission, again, to take into account the Union鈥檚 obligations under international agreements, such as the Paris Climate Agreement, the UN CBD and the UN Sustainable Development Goals, in the authorisation process;

7.听听Reiterates its call on the Commission to stop authorising GMOs, whether for cultivation or for food and feed uses, when no opinion is delivered by Member States in the Appeal Committee, in accordance with Article 6(3) of Regulation (EU) No听182/2011;

8.听听Reiterates its call on the Commission not to authorise herbicide-tolerant GM crops until the health risks associated with the residues have been comprehensively investigated on a case-by-case basis, which requires a full assessment of the residues from spraying such GM crops with complementary herbicides, an assessment of the herbicide break-down products and any combinatorial effects, including with the GM plant itself;

9.听听Calls on EFSA to finally accept the substantial differences between native Bt toxins and those expressed by synthetic transgenes in GM crop plants, and to widen its risk assessment in order to fully take into account all interactions and combinatorial effects between Bt toxins, GM plants and their constituents, residues from spraying with the complementary herbicides, the environment as well as impacts on health and food safety;

10.听听Calls on EFSA to no longer accept toxicity studies based on isolated proteins which are likely to be different in structure and biological effects compared to those produced by the plant itself, and to require that all tests are carried out with tissue from the GM plant;

11.听听Calls on EFSA to make sure that data from field trials or green houses cover a sufficiently broad range of agronomic and environmental conditions to assess the impact of all stress factors which have to be expected during cultivation on gene expression and plant composition;

12.听听Calls on EFSA to make sure that the data from field trials or green houses cover a sufficiently broad range of different varieties to assess the impact of various genetic backgrounds on gene expression and plant composition;

13.听听Calls on EFSA to request data on the impact of the consumption of food and feed derived from GM plants on the intestinal microbiome;

14.听听Instructs its President to forward this resolution to the Council and the Commission, and to the governments and parliaments of the Member States.

(1) OJ L 268, 18.10.2003, p. 1. (2) OJ L 55, 28.2.2011, p. 13. (3) https://www.efsa.europa.eu/en/efsajournal/pub/1075 (4) Scientific Opinion of the EFSA Panel on Genetically Modified Organisms on the assessment of genetically modified maize MON 88017 for renewal authorisation under Regulation (EC) No听1829/2003 (application EFSA鈥怗MO鈥怰X鈥�014). EFSA Journal 2020;18(3):6008, https://doi.org/10.2903/j.efsa.2020.6008. (5) 鈥撯�撯�撯�撯�撯�撯�撯�撯�撯�撯�� In its eighth term, the European 合法博彩网站 adopted 36 resolutions objecting to the authorisation of GMOs. Furthermore, in its ninth term 合法博彩网站 has adopted the following resolutions:European 合法博彩网站 resolution of 10 October 2019 on the draft Commission implementing decision authorising the placing on the market of products containing, consisting of or produced from genetically modified maize MZHG0JG (SYN-脴脴脴JG-2), pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2019)0028).European 合法博彩网站 resolution of 10 October 2019 on the draft Commission implementing decision renewing the authorisation for the placing on the market of products containing, consisting of or produced from genetically modified soybean A2704-12 (ACS-GM脴脴5-3) pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2019)0029).European 合法博彩网站 resolution of 10 October 2019 on the draft Commission implementing decision authorising the placing on the market of products containing, consisting of or produced from genetically modified maize MON 89034 脳 1507 脳 MON 88017 脳 59122 脳 DAS-40278-9 and genetically modified maize combining two, three or four of the single events MON 89034, 1507, MON 88017, 59122 and DAS-40278-9 pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2019)0030).European 合法博彩网站 resolution of 14 November 2019 on the draft Commission implementing decision renewing the authorisation for the placing on the market of products containing, consisting of or produced from genetically modified cotton LLCotton25 (ACS-GH脴脴1-3) pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2019)0054).European 合法博彩网站 resolution of 14 November 2019 on the draft Commission implementing decision renewing the authorisation for the placing on the market of products containing, consisting of or produced from genetically modified soybean MON 89788 (MON-89788-1) pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2019)0055).European 合法博彩网站 resolution of 14 November 2019 on the draft Commission implementing decision authorising the placing on the market of products containing, consisting of or produced from genetically modified maize MON 89034 脳 1507 脳 NK603 脳 DAS-40278-9 and sub-combinations MON 89034 脳 NK603 脳 DAS-40278-9, 1507 脳 NK603 脳 DAS-40278-9 and NK603 脳 DAS-40278-9 pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2019)0056).European 合法博彩网站 resolution of 14 November 2019 on the draft Commission implementing decision authorising the placing on the market of products containing, consisting of or produced from genetically modified maize Bt11 脳 MIR162 脳 MIR604 脳 1507 脳 5307 脳 GA21 and genetically modified maize combining two, three, four or five of the single events Bt11, MIR162, MIR604, 1507, 5307 and GA21 pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2019)0057).European 合法博彩网站 resolution of 14 May 2020 on the draft Commission implementing decision authorising the placing on the market of products containing, consisting of or produced from genetically modified soybean MON 87708 脳 MON 89788 脳 A5547-127, pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2020)0069).European 合法博彩网站 resolution of 11 November 2020 on the draft Commission implementing decision authorising the placing on the market of products containing, consisting of or produced from genetically modified maize MON 87427 脳 MON 89034 脳 MIR162 脳 NK603 and genetically modified maize combining two or three of the single events MON 87427, MON 89034, MIR162 and NK603, and repealing Commission Implementing Decision (EU) 2018/1111 pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2020)0291).European 合法博彩网站 resolution of 11 November 2020 on the draft Commission implementing decision authorising the placing on the market of products containing, consisting of or produced from genetically modified soybean SYHT0H2 (SYN-脴脴脴H2-5), pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2020)0292).European 合法博彩网站 resolution of 11 November 2020 on the draft Commission implementing decision authorising the placing on the market of products containing, consisting of or produced from genetically modified maize MON 87427 脳 MON 87460 脳 MON 89034 脳 MIR162 脳 NK603 and genetically modified maize combining two, three or four of the single events MON 87427, MON 87460, MON 89034, MIR162 and NK603, pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (Texts adopted, P9_TA(2020)0293). (6) Commission Decision 2009/814/EC of 30 October 2009 authorising the placing on the market of products containing, consisting of, or produced from genetically modified maize MON 88017 (MON-88脴17-3) pursuant to Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council (OJ L 289, 5.11.2009, p. 25). (7) EFSA opinion, p. 7 https://www.efsa.europa.eu/en/efsajournal/pub/1075 (8) Commission Implementing Regulation (EU) No听503/2013 of 3听April 2013 on applications for authorisation of genetically modified food and feed in accordance with Regulation (EC) No听1829/2003 of the European 合法博彩网站 and of the Council and amending Commission Regulations (EC) No听641/2004 and (EC) No听1981/2006 (OJ L 157, 8.6.2013, p. 1). (9) First set of Member State comments: http://registerofquestions.efsa.europa.eu/roqFrontend/questionLoader?question=EFSA-Q-2005-280 (10) Second set of Member State comments: http://registerofquestions.efsa.europa.eu/roqFrontend/questionLoader?question=EFSA-Q-2018-00672 (11) Directive 2001/18/EC of the European 合法博彩网站 and of the Council of 12 March 2001 on the deliberate release into the environment of genetically modified organisms and repealing Council Directive 90/220/EEC - Commission Declaration (OJ L 106, 17.4.2001, p. 1). (12) See, for example, Bonny, S., 鈥楪enetically Modified Herbicide-Tolerant Crops, Weeds, and Herbicides: Overview and Impact鈥�, Environmental Management. January 2016;57(1), pp. 31-48, https://www.ncbi.nlm.nih.gov/pubmed/26296738, and Benbrook, C.M., 鈥業mpacts of genetically engineered crops on pesticide use in the U.S. -- the first sixteen years鈥�, Environmental Sciences Europe 24, 24 (2012), https://enveurope.springeropen.com/articles/10.1186/2190-4715-24-24, and Sch眉tte, G., Eckerstorfer, M., Rastelli, V. et al., 鈥楬erbicide resistance and biodiversity: agronomic and environmental aspects of genetically modified herbicide-resistant plants鈥�, Environmental Sciences Europe 29, 5 (2017), https://enveurope.springeropen.com/articles/10.1186/s12302-016-0100-y (13) See, for example, https://www.sciencedirect.com/science/article/pii/S1383574218300887, https://academic.oup.com/ije/advance-article/doi/10.1093/ije/dyz017/5382278, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219610, and https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612199/ (14) The stacked GM maize contains an EPSPS modification. (15) EFSA Review of the existing maximum residue levels for glyphosate according to Article 12 of Regulation (EC) No听396/2005 鈥� revised version to take into account omitted data, EFSA Journal 2019;17(10):5862, p. 4, https://www.efsa.europa.eu/en/efsajournal/pub/5862 (16) EFSA Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate, EFSA journal 2015;13(11):4302, p. 3, https://www.efsa.europa.eu/en/efsajournal/pub/4302 (17) This is indeed the case for glyphosate, as stated in EFSA Review of the existing maximum residue levels for glyphosate according to Article 12 of Regulation (EC) No听396/2005, EFSA Journal 2018;16(5):5263, p. 12, https://www.efsa.europa.eu/fr/efsajournal/pub/5263 (18) MacIntosh, S.C., Kishore, G.M., Perlak, F.J., Marrone, P.G., Stone, T.B., Sims, S.R., Fuchs, R.L. 鈥楶otentiation of Bacillus thuringiensis insecticidal activity by serine protease inhibitors鈥�. J Agric Food Chem, 1990, 38: 1145-1152. (19) See, for example, Then, C. 鈥楻isk assessment of toxins derived from Bacillus thuringiensis: synergism, efficacy, and selectivity鈥�. Environ Sci Pollut Res Int, 2010, 17, pp. 791鈥�797. (20) See, for example, Han P, Niu CY, Lei CL, Cui JJ, Desneux N. 鈥楺uantification of toxins in a Cry1Ac听+听CpTI cotton cultivar and its potential effects on the honey bee Apis mellifera L.鈥櫶�Ecotoxicology. 2010, 19, pp. 1452-1459. https://link.springer.com/article/10.1007/s10646-010-0530-z Babendreier, D.,听Kalberer,N.M., Romeis, J.听Fluri, P.,听Mulligan, E.听and听Bigler, F., 鈥業nfluence of Bt-transgenic pollen, Bt-toxin and protease inhibitor (SBTI) ingestion on development of the hypopharyngeal glands in honeybees鈥�. Apidologie, 2005, 36 4, pp. 585-594, https://doi.org/10.1051/apido:2005049, and Liu, X.D., Zhai, B.P., Zhang, X.X., Zong, J.M. 鈥業mpact of transgenic cotton plants on a non-target pest, Aphis gossypii 骋濒辞惫别谤鈥�. Ecological Entomology, 30(3), pp. 307-315. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.0307-6946.2005.00690.x (21) For a review, see Rubio-Infante, N., Moreno-Fierros, L., 鈥楢n overview of the safety and biological effects of Bacillus thuringiensis Cry toxins in mammals鈥�, Journal of Applied Toxicology, May 2016, 36(5): pp. 630-648, http://onlinelibrary.wiley.com/doi/10.1002/jat.3252/full (22) See recital Q. (23) See, for example, Hilbeck, A. and Otto, M.. 鈥楽pecificity and combinatorial effects of Bacillus thuringiensis Cry toxins in the context of GMO risk assessment鈥�. Frontiers Environmental Science 2015, 3:71. (24) Hilbeck, A., Defarge, N., Lebrecht, T., B酶hn, T, 鈥業nsecticidal Bt crops. EFSA鈥檚 risk assessment approach for GM Bt plants fails by design鈥�, RAGES 2020, p. 4 https://www.testbiotech.org/sites/default/files/RAGES_report-Insecticidal%20Bt%20plants.pdf (25) https://www.dtnpf.com/agriculture/web/ag/crops/article/2020/09/29/epa-proposes-phasing-dozens-bt-corn (26) Douglas, M.R., Tooker, J.F., 鈥楲arge-Scale Deployment of Seed Treatments Has Driven Rapid Increase in Use of Neonicotinoid Insecticides and Preemptive Pest Management in U.S. Field Crops鈥�, Environmental Science and Technology 2015, 49, 8, pp. 5088-5097, https://pubs.acs.org/doi/10.1021/es506141g (27) Neonicotinoids,https://ec.europa.eu/food/plant/pesticides/approval_active_substances/approval_renewal/neonicotinoids_en (28) The Commission 鈥榤ay, and not 鈥榮hall鈥�, go ahead with authorisation if there is no qualified majority of Member States in favour at the Appeal Committee, according to Article 6(3) of Regulation (EU) No听182/2011. (29) Regulation (EC) No听178/2002 of the European 合法博彩网站 and of the Council of 28 January 2002 laying down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety (OJ L 31, 1.2.2002, p. 1). (30) https://tillymetz.lu/wp-content/uploads/2020/09/Co-signed-letter-MEP-Metz.pdf (31) MON 87708 脳 MON 89788 脳 A5547-127, https://webgate.ec.europa.eu/dyna/gm_register/gm_register_auth.cfm?pr_id=100